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犀利士 是什麼? 犀利士——他達拉非,是一個具選擇性、可逆的環狀單磷鳥糞核糖苷 (cyclic guanosine monophosphate, cGMP)- 特定的磷酸雙水解酶第五型 (phosphodiesterase type 5, PDE5)的抑制劑。當性刺激造成一氧化氮(nitric oxide)局部釋出時,tadalafil抑制PDE5的作用造成海綿體內cGMP的濃度增加,導致平滑肌放鬆和血流流入陰莖而勃起。若無性刺激,則犀利士沒有作用。 有三個臨床試驗進行,1054位病人在家評估對需要時服用犀利士的反應期。犀利士顯現在勃起功能的改善上具統計學意義且病人在服藥後最久至36小時,仍具有成功性交的能力,另外,相較於安慰劑,病人在服藥後最早16分鐘,已具有達到且維持勃起的能力以成功性*。 犀利士口溶型可以良好改善勃起功能,幫助患者成功完成性生活。犀利士獨具36小時穩定藥效,如果需要立即進行性生活,可在性生活前30分鐘服用。一般情況下,可在覺得方便時,口服一粒犀利士,服用後36小時內,可自由選擇任何時間段進行性生活,沒有時間壓力,在性刺激下享受自然的令雙方都滿意的性生活。而且藥效
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